Congo red inhibition of scrapie agent replication.
نویسندگان
چکیده
Congo red inhibits the accumulation of protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. Here we show that Congo red also inhibits the replication of scrapie infectivity in these cells. This observation is consistent with the idea that protease-resistant PrP is a vital component of the scrapie agent or that agent replication depends on the presence of protease-resistant PrP in the cell.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of virology
دوره 67 10 شماره
صفحات -
تاریخ انتشار 1993